The NELF Complex: A Potential Drug Target and Biomarker (P22586)

Target Name: NELF Complex

NCBI ID: P22586

NELF Complex

Other Name(s): None

The NELF Complex: A Potential Drug Target and Biomarker

The NELF Complex is a protein that plays a critical role in the regulation of mitochondrial function and energy metabolism. It is a multi-subunit protein complex composed of various subunits that are involved in the processes of energy metabolism, such as metabolism, Oxidative phosphorylation, and cellular stress response. The NELF Complex is also involved in the regulation of mitochondrial dynamics, including the dynamics of mitochondrial fusion and fission, as well as the regulation of mitochondrial fusion and fission.

The NELF Complex is a protein that is expressed in most cell types of higher eukaryotes, including mammals, birds, fish, and plants. It is also found in various organelles, including the mitochondria, where it plays a critical role in the regulation of mitochondrial function and energy metabolism.

The NELF Complex is involved in the regulation of a wide range of cellular processes that are critical for the survival of cells. It is involved in the metabolism of fatty acids, which are essential for the maintenance of cellular energy homeostasis. The NELF Complex is also involved in the regulation of the levels of reactive oxygen species (ROS) in cells, which can damage cellular components and contribute to the development of cellular stress.

The NELF Complex is composed of multiple subunits that are involved in the regulation of different cellular processes. The most well-studied subunit of the NELF Complex is the NELF-1 subunit, which is responsible for the regulation of the levels of acetyl-CoA in the cytosol of the cell. The NELF-1 subunit is involved in the regulation of the citric acid cycle, which is the central metabolic pathway of the cell that is responsible for the production of energy from the metabolism of fatty acids.

The NELF-1 subunit of the NELF Complex is also involved in the regulation of the levels of ROS in the cell. ROS are reactive oxygen species that can damage cellular components and contribute to the development of cellular stress. in the regulation of the production and degradation of ROS, which allows the cell to maintain a balance between the production of ROS and its degradation.

Another subunit of the NELF Complex is the NELF-2 subunit, which is involved in the regulation of the levels of succinyl-CoA in the cytosol of the cell. The NELF-2 subunit is involved in the regulation of the citric acid cycle, which is the central metabolic pathway of the cell that is responsible for the production of energy from the metabolism of fatty acids.

The NELF-3 subunit of the NELF Complex is involved in the regulation of the levels of fumarate in the cytosol of the cell. Fumarate is a derivative of furin, which is a protein that is involved in the regulation of cell wall formation. -3 subunit is involved in the regulation of the production and degradation of fumarate, which allows the cell to maintain a balance between the production of fumarate and its degradation.

The NELF-4 subunit of the NELF Complex is involved in the regulation of the levels of ubiquitin in the cytosol of the cell. Ubiquitin is a protein that is involved in the regulation of cellular signaling pathways, including the regulation of cell growth and The NELF-4 subunit is involved in the differentiation of the production and degradation of ubiquitin, which allows the cell to maintain a balance between the production of ubiquitin and its degradation.

The NELF-5 subunit of the NELF Complex is involved in the regulation of the levels of

Protein Name: NELF Complex

The "NELF Complex Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NELF Complex comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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